Structure of PDB 2a83 Chain A

Receptor sequence
>2a83A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFHTSVSRPGRGEPRFITVGYVDDTLFVRFDSDAASPREEPRAP
WIEQEGPEYWDRETQICKAKAQTDREDLRTLLRYYNQSEAGSHTLQNMYG
CDVGPDGRLLRGYHQDAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQLRAYLEGECVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB2a83 Conformational dimorphism of self-peptides and molecular mimicry in a disease-associated HLA-B27 subtype.
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 H9 T24 E45 R62 E63 Q65 I66 C67 K70 T73 E76 D77 Y84 Y99 T143 K146 W147 V152 L156 Y159 E163 W167 Y171 Y7 H9 T24 E45 R62 E63 Q65 I66 C67 K70 T73 E76 D77 Y84 Y99 T143 K146 W147 V152 L156 Y159 E163 W167 Y171
External links
PDB RCSB:2a83, PDBe:2a83, PDBj:2a83
PDBsum2a83
PubMed16221670
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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