Structure of PDB 2a65 Chain A

Receptor sequence
>2a65A (length=509) Species: 224324 (Aquifex aeolicus VF5) [Search protein sequence]
REHWATRLGLILAMAGNAVGLGNFLRFPVQAAENGGGAFMIPYIIAFLLV
GIPLMWIEWAMGRYGGAQGHGTTPAIFYLLWRNRFAKILGVFGLWIPLVV
AIYYVYIESWTLGFAIKFLVGLVPEPPPTDPDSILRPFKEFLYSYIGVPK
GDEPILKPSLFAYIVFLITMFINVSILIRGISKGIERFAKIAMPTLFILA
VFLVIRVFLLETPNGTAADGLNFLWTPDFEKLKDPGVWIAAVGQIFFTLS
LGFGAIITYASYVRKDQDIVLSGLTAATLNEKAEVILGGSISIPAAVAFF
GVANAVAIAKAGAFNLGFITLPAIFSQTAGGTFLGFLWFFLLFFAGLTSS
IAIMQPMIAFLEDELKLSRKHAVLWTAAIVFFSAHLVMFLNKSLDEMDFW
AGTIGVVFFGLTELIIFFWIFGADKAWEEINRGGIIKVPRIYYYVMRYIT
PAFLAVLLVVWAREYIPKIMEETHWTVWITRFYIIGLFLFLTFLVFLAER
RRNHESAGT
3D structure
PDB2a65 Crystal structure of a bacterial homologue of Na(+)/Cl(-)-dependent neurotransmitter transporters.
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NA A G20 V23 G24 A351 T354 S355 G16 V19 G20 A345 T348 S349
BS02 NA A A22 V23 N27 T254 N286 A18 V19 N23 T248 N280
BS03 LEU A N21 A22 G24 L25 G26 Y108 F253 T254 S256 F259 I359 N17 A18 G20 L21 G22 Y104 F247 T248 S250 F253 I353
Gene Ontology
Biological Process
GO:0035725 sodium ion transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:2a65, PDBe:2a65, PDBj:2a65
PDBsum2a65
PubMed16041361
UniProtO67854

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