Structure of PDB 2a3v Chain A

Receptor sequence

>2a3vA (length=313) Species: 243277 (Vibrio cholerae O1 biovar El Tor str. N16961) [Search protein sequence]

GSQFLLSVREFMQTRYYAKKTIEAYLHWITRYIHFHNKKHPSLMGDKEVE
EFLTYLAVQGKVATKTQSLALNSLSFLYKEILKTPLSLEIRFQRSQLERK
LPVVLTRDEIRRLLEIVDPKHQLPIKLLYGSGLRLMECMRLRVQDIDFDY
GAIRIWQGKGGKNRTVTLAKELYPHLKEQIALAKRYYDRDLHQKNYGGVW
LPTALKEKYPNAPYEFRWHYLFPSFQLSLDPESDVMRRHHMNETVLQKAV
RRSAQEAGIEKTVTCHTLRHSFATHLLEVGADIRTVQEQLGHTDVKTTQI
YTHSGVLSPLSRL

3D structure

PDB

2a3v Structural basis for broad DNA-specificity in integron recombination.

Chain

Resolution

2.8 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	H28 R32 A64 K66 T67 K160 H267 H293 T294 K297 T298 Y302	H27 R31 A63 K65 T66 K159 H266 H292 T293 K296 T297 Y301
BS02	dna	A	Y18 A19 K21 T22 Y26 T65 S69 L70 L72 N73 S76 K80 S88 L89 I91 R95 M137 K160 Q248 T265 C266 H267	Y17 A18 K20 T21 Y25 T64 S68 L69 L71 N72 S75 K79 S87 L88 I90 R94 M136 K159 Q247 T264 C265 H266
BS03	dna	A	K209 Y210	K208 Y209
BS04	dna	A	W157 T204 A205 K209 Y210 W219	W156 T203 A204 K208 Y209 W218

Gene Ontology

	Molecular Function
GO:0003677	DNA binding

	Biological Process
GO:0006310	DNA recombination
GO:0015074	DNA integration

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:2a3v, PDBe:2a3v, PDBj:2a3v
PDBsum	2a3v
PubMed	16641988
UniProt	O68847

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