Structure of PDB 2a3i Chain A

Receptor sequence
>2a3iA (length=253) Species: 9606 (Homo sapiens) [Search protein sequence]
RALTPSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVV
KWAKVLPGFKNLPLEDQITLIQYSWMSLSSFALSWRSYKHTNSQFLYFAP
DLVFNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTI
PKDGLKSQAAFEEMRTNYIKELRKMVTKCPNNSGQSWQRFYQLTKLLDSM
HDLVSDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYF
HRK
3D structure
PDB2a3i Structural and biochemical mechanisms for the specificity of hormone binding and coactivator assembly by mineralocorticoid receptor
ChainA
Resolution1.95 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V781 K782 K785 L795 I799 M959 E962 V50 K51 K54 L64 I68 M228 E231
BS02 C0R A L766 L769 N770 A773 Q776 M807 S810 F829 M845 M852 F941 T945 L35 L38 N39 A42 Q45 M76 S79 F98 M114 M121 F210 T214 BindingDB: Kd=0.500000nM
External links
PDB RCSB:2a3i, PDBe:2a3i, PDBj:2a3i
PDBsum2a3i
PubMed16061183
UniProtP08235|MCR_HUMAN Mineralocorticoid receptor (Gene Name=NR3C2)

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