Structure of PDB 2a1y Chain A

Receptor sequence
>2a1yA (length=301) Species: 1392 (Bacillus anthracis) [Search protein sequence]
MGNVFDYEDIQLIPAKCIVNSRSECDTTVTLGKHKFKLPVVPANMQTIID
ERIATYLAENNYFYIMHRFQPEKRISFIRDMQSRGLIASISVGVKEDEYE
FVQQLAAEHLTPEYITIDIAHGHSNAVINMIQHIKKHLPESFVIAGNVGT
PEAVRELENAGADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAA
SKPIIADGGIRTNGDVAKSIRFGATMVMIGSLFAGHEESPGETIEKLYKE
YFGSFVEHKGSLEDTLIEMEQDLQSSISYAGGTKLDSIRTVDYVVVKNSI
F
3D structure
PDB2a1y Crystal structure of GuaC-GMP complex from Bacillus anthracis at 2.26 A resolution.
ChainA
Resolution2.27 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.7.1.7: GMP reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5GP A A43 M45 G172 K173 C175 D207 M228 G230 S231 G256 A43 M45 G172 K173 C175 D207 M228 G230 S231 G253
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0003920 GMP reductase activity
GO:0016491 oxidoreductase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
Biological Process
GO:0006163 purine nucleotide metabolic process
GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process
Cellular Component
GO:0005829 cytosol
GO:1902560 GMP reductase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2a1y, PDBe:2a1y, PDBj:2a1y
PDBsum2a1y
PubMed
UniProtQ81JJ9|GUAC_BACAN GMP reductase (Gene Name=guaC)

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