Structure of PDB 2a11 Chain A

Receptor sequence
>2a11A (length=154) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
IRSRQPLLDALGVDLPDELLSLALTHRSYAYENGGLPTNERLEFLGDAVL
GLTITDALFHRHPDRSEGDLAKLRASVVNTQALADVARRLCAEGLGVHVL
LGRGEANTGGADKSSILADGMESLLGAIYLQHGMEKAREVILRLFGPLLD
AAPT
3D structure
PDB2a11 Structure of the nuclease domain of ribonuclease III from M. tuberculosis at 2.1 A
ChainA
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.26.3: ribonuclease III.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E44 E123 E43 E122
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0004519 endonuclease activity
GO:0004521 RNA endonuclease activity
GO:0004525 ribonuclease III activity
GO:0046872 metal ion binding
Biological Process
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0006397 mRNA processing
GO:0008033 tRNA processing
GO:0010468 regulation of gene expression
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2a11, PDBe:2a11, PDBj:2a11
PDBsum2a11
PubMed16155207
UniProtP9WH03|RNC_MYCTU Ribonuclease 3 (Gene Name=rnc)

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