Structure of PDB 2a0s Chain A

Receptor sequence
>2a0sA (length=163) Species: 5855 (Plasmodium vivax) [Search protein sequence]
DQIAELLVESPLFSFNCAHFIAFKGFRETLHGHNYNVSLRLRGNIQGDGY
VIDFSILKEKVRKVCKQLDHHFILPMYSDVLNIQEVNDNFKITCEDNSEY
SFPKRDCVQIPIKHSSTEEIGLYILNQLIEEIDLPFLKTRSVNYMEVTVS
ESPSQKATVHRNI
3D structure
PDB2a0s Crystal structure of 6-pyruvoyl tetrahydropterin synthase (PTPS) from Plasmodium vivax at 2.2 A resolution
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.2.3.12: 6-pyruvoyltetrahydropterin synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H36 H48 H50 E168 H19 H31 H33 E151
BS02 BIO A E45 T134 E135 E168 E28 T117 E118 E151
Gene Ontology
Molecular Function
GO:0003874 6-pyruvoyltetrahydropterin synthase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0006729 tetrahydrobiopterin biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:2a0s, PDBe:2a0s, PDBj:2a0s
PDBsum2a0s
PubMed
UniProtA5K2B2

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