Structure of PDB 1ztw Chain A

Receptor sequence
>1ztwA (length=255) Species: 11801 (Moloney murine leukemia virus) [Search protein sequence]
TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLG
IKPHIQRLLDQGILVPCQSPWNTPLLPVKKPGTNDYRPVQDLREVNKRVE
DIHPTVPNPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWR
DPEMGISGQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYV
DDLLLAATSELDCQQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLL
KEGQR
3D structure
PDB1ztw A host-guest approach for determining drug-DNA interactions: an example using netropsin.
ChainA
Resolution1.8 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A Y64 L99 R116 Y41 L76 R93
BS02 dna A L99 D114 L115 R116 G191 L76 D91 L92 R93 G168
External links
PDB RCSB:1ztw, PDBe:1ztw, PDBj:1ztw
PDBsum1ztw
PubMed16049022
UniProtP03355|POL_MLVMS Gag-Pol polyprotein (Gene Name=gag-pol)

[Back to BioLiP]