Structure of PDB 1zs5 Chain A

Receptor sequence
>1zs5A (length=118) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHMSKEPRDPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVI
RFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNPPESEYYKCAN
ILEKFFFSKIKEAGLIDK
3D structure
PDB1zs5 Structure-based evaluation of selective nad non-selective small molecules that block hiv-1 tat and pcaf association
ChainA
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.48: histone acetyltransferase.
2.3.1.57: diamine N-acetyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MIB A F748 V752 E756 A757 Y760 M768 D769 N798 Y802 F34 V38 E42 A43 Y46 M54 D55 N84 Y88
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:1zs5, PDBe:1zs5, PDBj:1zs5
PDBsum1zs5
PubMed
UniProtQ92831|KAT2B_HUMAN Histone acetyltransferase KAT2B (Gene Name=KAT2B)

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