Structure of PDB 1zrm Chain A

Receptor sequence
>1zrmA (length=220) Species: 66693 (Pseudomonas sp. YL) [Search protein sequence]
YIKGIAFDLYGTLFDVHSVVGRCDEAFPGRGREISALWRQKQLEYTWLRS
LMNRYVNFQQATEDALRFTCRHLGLDLDARTRSTLCDAYLRLAPFSEVPD
SLRELKRRGLKLAILSNGSPQSIDAVVSHAGLRDGFDHLLSVDPVQVYKP
DNRVYELAEQALGLDRSAILFVASNAWDATGARYFGFPTCWINRTGNVFE
EMGQTPDWEVTSLRAVVELF
3D structure
PDB1zrm Crystal structures of reaction intermediates of L-2-haloacid dehalogenase and implications for the reaction mechanism.
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) D10 T14 R41 S118 N119 K151 A175 N177 W179 D180
Catalytic site (residue number reindexed from 1) D8 T12 R39 S116 N117 K149 A173 N175 W177 D178
Enzyme Commision number 3.8.1.2: (S)-2-haloacid dehalogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BUA A D10 L11 Y12 S118 D8 L9 Y10 S116
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0018784 (S)-2-haloacid dehalogenase activity
GO:0019120 hydrolase activity, acting on acid halide bonds, in C-halide compounds

View graph for
Molecular Function
External links
PDB RCSB:1zrm, PDBe:1zrm, PDBj:1zrm
PDBsum1zrm
PubMed9614112
UniProtQ53464|HAD_PSEUY (S)-2-haloacid dehalogenase

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