Structure of PDB 1zk4 Chain A

Receptor sequence
>1zk4A (length=251) Species: 1580 (Levilactobacillus brevis) [Search protein sequence]
SNRLDGKVAIITGGTLGIGLAIATKFVEEGAKVMITGRHSDVGEKAAKSV
GTPDQIQFFQHDSSDEDGWTKLFDATEKAFGPVSTLVNNAGIAVNKSVEE
TTTAEWRKLLAVNLDGVFFGTRLGIQRMKNKGLGASIINMSSIEGFVGDP
SLGAYNASKGAVRIMSKSAALDCALKDYDVRVNTVHPGYIKTPLVDDLPG
AEEAMSQRTKTPMGHIGEPNDIAYICVYLASNESKFATGSEFVVDGGYTA
Q
3D structure
PDB1zk4 Atomic Resolution Structures of R-specific Alcohol Dehydrogenase from Lactobacillus brevis Provide the Structural Bases of its Substrate and Cosubstrate Specificity
ChainA
Resolution1.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) G17 S142 Y155 K159
Catalytic site (residue number reindexed from 1) G17 S142 Y155 K159
Enzyme Commision number 1.1.1.2: alcohol dehydrogenase (NADP(+)).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP A G13 T15 L16 I18 T36 G37 R38 H61 D62 N89 A90 G91 I92 Y155 G188 I190 T192 L194 G13 T15 L16 I18 T36 G37 R38 H61 D62 N89 A90 G91 I92 Y155 G188 I190 T192 L194
BS02 AC0 A A93 Y155 Y189 A93 Y155 Y189
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:1zk4, PDBe:1zk4, PDBj:1zk4
PDBsum1zk4
PubMed15896805
UniProtQ84EX5

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