Structure of PDB 1zip Chain A

Receptor sequence
>1zipA (length=217) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence]
MNLVLMGLPGAGKGTQAEKIVAAYGIPHISTGDMFRAAMKEGTPLGLQAK
QYMDRGDLVPDEVTIGIVRERLSKDDCQNGFLLDGFPRTVAQAEALETML
ADIGRKLDYVIHIDVRQDVLMERLTGRRICRNCGATYHLIFHPPAKPGVC
DKCGGELYQRADDNEATVANRLEVNMKQMKPLVDFYEQKGYLRNINGEQD
MEKVFADIRELLGGLAR
3D structure
PDB1zip Crystal structures of Bacillus stearothermophilus adenylate kinase with bound Ap5A, Mg2+ Ap5A, and Mn2+ Ap5A reveal an intermediate lid position and six coordinate octahedral geometry for bound Mg2+ and Mn2+.
ChainA
Resolution1.85 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) K13 R88 R127 R160 R171
Catalytic site (residue number reindexed from 1) K13 R88 R127 R160 R171
Enzyme Commision number 2.7.4.3: adenylate kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A C130 C133 C150 C153 C130 C133 C150 C153
BS02 AP5 A P9 G10 G12 K13 G14 T15 T31 G32 F35 R36 M53 D57 L58 V59 T64 R88 Q92 R123 R127 F141 R160 R171 M201 P9 G10 G12 K13 G14 T15 T31 G32 F35 R36 M53 D57 L58 V59 T64 R88 Q92 R123 R127 F141 R160 R171 M201
Gene Ontology
Molecular Function
GO:0004017 adenylate kinase activity
GO:0004550 nucleoside diphosphate kinase activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0016301 kinase activity
GO:0016776 phosphotransferase activity, phosphate group as acceptor
GO:0019205 nucleobase-containing compound kinase activity
GO:0046872 metal ion binding
GO:0050145 nucleoside monophosphate kinase activity
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0009123 nucleoside monophosphate metabolic process
GO:0009132 nucleoside diphosphate metabolic process
GO:0009165 nucleotide biosynthetic process
GO:0016310 phosphorylation
GO:0044209 AMP salvage
GO:0046940 nucleoside monophosphate phosphorylation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1zip, PDBe:1zip, PDBj:1zip
PDBsum1zip
PubMed9715904
UniProtP27142|KAD_GEOSE Adenylate kinase (Gene Name=adk)

[Back to BioLiP]