Structure of PDB 1zht Chain A

Receptor sequence
>1zhtA (length=436) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
MDPSQYASSSSWTSFLKSIASFNGDLSSLSAPPFILSPISLTEFSQYWAE
HPELFLEPSFINDDNYKEHCLIDPEVESPELARMLAVTKWFISTLKSQYC
SRNESLGSEKKPLNPFLGELFVGKWENKEHPEFGETVLLSEQVSHHPPVT
AFSIFNDKNKVKLQGYNQIKASFTKSLMLTVKQFGHTMLDIKDESYLVTP
PPLHIEGILVASPFVELEGKSYIQSSTGLLCVIEFSGRGYFSGKKNSFKA
RIYKDSKDSKDKEKALYTISGQWSGSSKIIKANKKEESRLFYDAARIPAE
HLNVKPLEEQHPLESRKAWYDVAGAIKLGDFNLIAKTKTELEETQRELRK
EEEAKGISWQRRWFKDFDYSVTPEEGALVPEKDDTFLKLASALNLSTKNA
PSGTLVGDKEDRKEDLSSIHWRFQRELWDEEKEIVL
3D structure
PDB1zht Structural mechanism for sterol sensing and transport by OSBP-related proteins
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HCR A F42 Q96 Y97 R100 E107 N165 F44 Q98 Y99 R102 E109 N167
Gene Ontology
Molecular Function
GO:0005546 phosphatidylinositol-4,5-bisphosphate binding
GO:0008142 oxysterol binding
GO:0008289 lipid binding
GO:0070273 phosphatidylinositol-4-phosphate binding
GO:0070300 phosphatidic acid binding
GO:0120015 sterol transfer activity
Biological Process
GO:0006665 sphingolipid metabolic process
GO:0006869 lipid transport
GO:0006887 exocytosis
GO:0006892 post-Golgi vesicle-mediated transport
GO:0006897 endocytosis
GO:0015918 sterol transport
GO:0030011 maintenance of cell polarity
GO:0034727 piecemeal microautophagy of the nucleus
GO:0035621 ER to Golgi ceramide transport
Cellular Component
GO:0000139 Golgi membrane
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1zht, PDBe:1zht, PDBj:1zht
PDBsum1zht
PubMed16136145
UniProtP35844|KES1_YEAST Oxysterol-binding protein homolog 4 (Gene Name=KES1)

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