Structure of PDB 1zh5 Chain A

Receptor sequence
>1zh5A (length=185) Species: 9606 (Homo sapiens) [Search protein sequence]
GDNEKMAALEAKICHQIEYYFGDFNLPRDKFLKEQIKLDEGWVPLEIMIK
FNRLNRLTTDFNVIVEALSKSKAELMEISEDKTKIRRSPSKPLPEVTDEY
KNDVKNRSVYIKGFPTDATLDDIKEWLEDKGQVLNIQMRRTLHKAFKGSI
FVVFDSIESAKKFVETPGQKYKETDLLILFKDDYF
3D structure
PDB1zh5 Structural Basis for Recognition and Sequestration of UUU(OH) 3' Temini of Nascent RNA Polymerase III Transcripts by La, a Rheumatic Disease Autoantigen.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A F28 V108 Q141 K185 F24 V104 Q137 K181 PDBbind-CN: Kd=7nM
BS02 rna A Y23 Y24 D33 F55 N56 R57 I140 Y19 Y20 D29 F51 N52 R53 I136 PDBbind-CN: Kd=7nM
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
Biological Process
GO:0006396 RNA processing
Cellular Component
GO:0005634 nucleus
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1zh5, PDBe:1zh5, PDBj:1zh5
PDBsum1zh5
PubMed16387655
UniProtP05455|LA_HUMAN Lupus La protein (Gene Name=SSB)

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