Structure of PDB 1zg7 Chain A

Receptor sequence
>1zg7A (length=305) Species: 9823 (Sus scrofa) [Search protein sequence]
TGHSYEKYNNWETIEAWTKQVTSENPDLISRTAIGTTFLGNNIYLLKVGK
PGPNKPAIFMDCGFHAREWISHAFCQWFVREAVLTYGYESHMTEFLNKLD
FYVLPVLNIDGYIYTWTKNRMWRKTRSTNAGTTCIGTDPNRNFDAGWCTT
GASTDPCDETYCGSAAESEKETKALADFIRNNLSSIKAYLTIHSYSQMIL
YPYSYDYKLPENNAELNNLAKAAVKELATLYGTKYTYGPGATTIYPAAGG
SDDWAYDQGIKYSFTFELRDKGRYGFILPESQIQATCEETMLAIKYVTNY
VLGHL
3D structure
PDB1zg7 Crystal structures of potent thiol-based inhibitors bound to carboxypeptidase b.
ChainA
Resolution1.75 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H69 E72 R127 H196 E270
Catalytic site (residue number reindexed from 1) H65 E68 R123 H193 E267
Enzyme Commision number 3.4.17.2: carboxypeptidase B.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H69 E72 H196 H65 E68 H193
BS02 P20 A H69 R127 N144 R145 H196 L203 S207 D255 E270 H65 R123 N140 R141 H193 L200 S204 D252 E267
Gene Ontology
Molecular Function
GO:0004181 metallocarboxypeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1zg7, PDBe:1zg7, PDBj:1zg7
PDBsum1zg7
PubMed15982000
UniProtP09955|CBPB1_PIG Carboxypeptidase B (Gene Name=CPB1)

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