Structure of PDB 1zbl Chain A

Receptor sequence
>1zblA (length=133) Species: 272558 (Halalkalibacterium halodurans C-125) [Search protein sequence]
EEIIWESLSVDVGSQGNPGIVEYKGVDTKTGEVLFEREPIPIGTNNMGEF
LAIVHGLRYLKERNSRKPIYSDSQTAIKWVKDKKAKSTLVRNEETALIWK
LVDEAEEWLNTHTYETPILKWQTDKWGEIKANY
3D structure
PDB1zbl Crystal Structures of RNase H Bound to an RNA/DNA Hybrid: Substrate Specificity and Metal-Dependent Catalysis.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.26.4: ribonuclease H.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A D71 G73 S74 Q75 G76 N105 E109 D132 Q134 K180 T183 D11 G13 S14 Q15 G16 N45 E49 D72 Q74 K120 T123
BS02 dna A N77 T104 N105 N106 T135 W139 S147 T148 N17 T44 N45 N46 T75 W79 S87 T88
BS03 MG A D71 E109 D132 D11 E49 D72
BS04 MG A D71 N192 D11 N132
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004523 RNA-DNA hybrid ribonuclease activity

View graph for
Molecular Function
External links
PDB RCSB:1zbl, PDBe:1zbl, PDBj:1zbl
PDBsum1zbl
PubMed15989951
UniProtQ9KEI9|RNH1_HALH5 Ribonuclease H (Gene Name=rnhA)

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