Structure of PDB 1zb7 Chain A

Receptor sequence
>1zb7A (length=414) Species: 1491 (Clostridium botulinum) [Search protein sequence]
PVNIKNFNYNDPINNDDIIMMEPFNDPGPGTYYKAFRIIDRIWIVPERFT
YKDVYEYYDPTYLKTDAEKDKFLKTMIKLFNRINSKPSGQRLLDMIVDAI
PYLGNASTPPDKFAANVANVSINKKIIQPGAEDQIKGLMTNLIIFGPGPV
LSDNFTDSMIMNGHSPISEGFGARMMIRFCPSCLNVFNNVQENKIFSRRA
YFADPALTLMHELIHVLHGLYGIKISNLPITPFMQHSDPVQAEELYTFGG
HDPSVISPSTDMNIYNKALQNFQDIANRLNIVSSAQGSGIDISLYKQIYK
NKYDFVEDPNGKYSVDKDKFDKLYKALMFGFTETNLAGEYGIKTRYSYFS
EYLPPIKTEKLLDNTIYTQNEGFNIASKNLKTEFNGQNKAVNKEAYEEIS
LEHLVIYRIAMCKP
3D structure
PDB1zb7 Crystal structure of botulinum neurotoxin type g light chain: serotype divergence in substrate recognition
ChainA
Resolution2.35 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H230 E231 H234 E268 R369
Catalytic site (residue number reindexed from 1) H211 E212 H215 E244 R345
Enzyme Commision number 3.4.24.69: bontoxilysin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H230 H234 H211 H215
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1zb7, PDBe:1zb7, PDBj:1zb7
PDBsum1zb7
PubMed16008342
UniProtQ60393|BXG_CLOBO Botulinum neurotoxin type G (Gene Name=botG)

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