Structure of PDB 1za0 Chain A

Receptor sequence
>1za0A (length=242) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
DALTLELEPVVEANMTRHLDTEDIWFAHDYVPFDQGENFAFLGGRDWDPS
QSTLPRTITDACEILLILKDNDWWGRWLGRWTAEEHLHAIALREYLVVTR
EVDPVANEDVRVKYTQVETLVYMAFYERCGAVFCRNLAAQIEEPILAGLI
DRIARDEVRHEEFFANLVTHCLDYTRDETIAAIAARAADLDVLGADIEAY
RDKLQNVADAGIFGKPQLRQLISDRITAWGLAGEPSLKQFVT
3D structure
PDB1za0 X-ray structure of putative acyl-ACP desaturase DesA2 from Mycobacterium tuberculosis H37Rv.
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) W32
Catalytic site (residue number reindexed from 1) W25
Enzyme Commision number 1.14.19.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A E107 E159 E189 H192 E85 E127 E157 H160
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016491 oxidoreductase activity
GO:0045300 stearoyl-[ACP] desaturase activity
GO:0046872 metal ion binding
Biological Process
GO:0006631 fatty acid metabolic process
GO:0006633 fatty acid biosynthetic process
Cellular Component
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1za0, PDBe:1za0, PDBj:1za0
PDBsum1za0
PubMed15929999
UniProtP9WNZ5|DESA2_MYCTU Putative acyl-[acyl-carrier-protein] desaturase DesA2 (Gene Name=desA2)

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