Structure of PDB 1z97 Chain A

Receptor sequence
>1z97A (length=263) Species: 9606 (Homo sapiens) [Search protein sequence]
EWGYASHNGPDHWHELFPNAKGENQSPIELHTKDIRHDPSLQPWSVSYDG
GSAKTILNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDH
GSEHTVDGVKYAAELHLVHWNPKYNTFKEALKQRDGIAVIGIFLKIGHEN
GEFQIFLDALDKIKTKGKEAPFTKFDPSSLFPASRDYWTYQGSLTTPPCE
ECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSNWRPPQPINNR
VVRASFKHHHHHH
3D structure
PDB1z97 Human Carbonic Anhydrase III: Structural and Kinetic Study of Catalysis and Proton Transfer
ChainA
Resolution2.1 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K64 H94 H96 E106 H119 T199
Catalytic site (residue number reindexed from 1) K61 H91 H93 E103 H116 T195
Enzyme Commision number 4.2.1.1: carbonic anhydrase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H94 H96 H119 H91 H93 H116
Gene Ontology
Molecular Function
GO:0004089 carbonate dehydratase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016151 nickel cation binding
GO:0016829 lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0006730 one-carbon metabolic process
GO:0009617 response to bacterium
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1z97, PDBe:1z97, PDBj:1z97
PDBsum1z97
PubMed16042381
UniProtP07451|CAH3_HUMAN Carbonic anhydrase 3 (Gene Name=CA3)

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