Structure of PDB 1z84 Chain A

Receptor sequence

>1z84A (length=311) Species: 3702 (Arabidopsis thaliana)

SPELRKDPVTNRWVIFSPRPTDFKSKSPSSCPFCIGREQECAPELFRVPD
HDPNWKLRVIENLYPALSRNLETQSRTIVGFGFHDVVIESPVHSIQLSDI
DPVGIGDILIAYKKRINQIAQHDSINYIQVFKNQGASAGASMSHSHSQMM
ALPVVPPTVSSRLDGTKDYFEETGKCCLCEAKSKHFVIDESSHFVSVAPF
AATYPFEIWIIPKDHSSHFHHLDDVKAVDLGGLLKLMLQKIAKQLNDPPY
NYMIHTSPLKVTESQLPYTHWFLQIVPQLSGVGGFEIGTGCYINPVFPED
VAKVMREVSLT

3D structure

• PDB: 1z84 Structure and Mechanism of an ADP-Glucose Phosphorylase from Arabidopsis thaliana
• Chain: A
• Resolution: 1.83 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): C63 C66 H133 N173 S181 H184 H186 Q188
• Catalytic site (residue number reindexed from 1): C31 C34 H93 N133 S141 H144 H146 Q148
• Enzyme Commision number: 2.7.7.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	ZN	A	C63 C66 H133 H184	C31 C34 H93 H144
BS02	ZN	A	C216 C219 H255 H310	C176 C179 H215 H270
BS03	AMP	A	F65 N94 L95 Y96 N173 A180 S181 M182 H186 Q188	F33 N62 L63 Y64 N133 A140 S141 M142 H146 Q148

Gene Ontology

Molecular Function

• GO:0008108 UDP-glucose:hexose-1-phosphate uridylyltransferase activity
• GO:0008270 zinc ion binding
• GO:0016779 nucleotidyltransferase activity
• GO:0017103 UTP:galactose-1-phosphate uridylyltransferase activity
• GO:0043531 ADP binding
• GO:0046872 metal ion binding
• GO:0047345 ribose-5-phosphate adenylyltransferase activity

Biological Process

• GO:0005975 carbohydrate metabolic process
• GO:0006006 glucose metabolic process
• GO:0006012 galactose metabolic process
• GO:0080040 positive regulation of cellular response to phosphate starvation

External links

• PDB: RCSB:1z84, PDBe:1z84, PDBj:1z84
• PDBsum: 1z84
• PubMed: 16519510
• UniProt: Q9FK51|AGLUP_ARATH ADP-glucose phosphorylase (Gene Name=At5g18200)