Structure of PDB 1z82 Chain A

Receptor sequence
>1z82A (length=312) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]
EMRFFVLGAGSWGTVFAQMLHENGEEVILWARRKEIVDLINVSHTSPYVE
ESKITVRATNDLEEIKKEDILVIAIPVQYIREHLLRLPVKPSMVLNLSKG
IEIKTGKRVSEIVEEILGCPYAVLSGPSHAEEVAKKLPTAVTLAGENSKE
LQKRISTEYFRVYTCEDVVGVEIAGALKNVIAIAAGILDGFGGWDNAKAA
LETRGIYEIARFGMFFGADQKTFMGLAGIGDLMVTCNSRYSRNRRFGELI
ARGFNPLKLLESSNQVVEGAFTVKAVMKIAKENKIDMPISEEVYRVVYEG
KPPLQSMRDLMR
3D structure
PDB1z82 Crystal structure of glycerol-3-phosphate dehydrogenase (TM0378) from Thermotoga maritima at 2.00 A resolution
ChainA
Resolution2.0 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) K179 T236
Catalytic site (residue number reindexed from 1) K178 T235
Enzyme Commision number 1.1.1.94: glycerol-3-phosphate dehydrogenase [NAD(P)(+)].
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NDP A G11 S12 W13 R33 R34 Y49 P77 Y80 S99 K100 S129 H130 A131 R243 Q266 E269 G10 S11 W12 R32 R33 Y48 P76 Y79 S98 K99 S128 H129 A130 R242 Q265 E268
BS02 G3P A K100 S129 H130 K179 D232 S242 R243 N244 K99 S128 H129 K178 D231 S241 R242 N243
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0047952 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GO:0051287 NAD binding
GO:0141153 glycerol-3-phosphate dehydrogenase (NADP+) activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006072 glycerol-3-phosphate metabolic process
GO:0006650 glycerophospholipid metabolic process
GO:0008654 phospholipid biosynthetic process
GO:0046167 glycerol-3-phosphate biosynthetic process
GO:0046168 glycerol-3-phosphate catabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1z82, PDBe:1z82, PDBj:1z82
PDBsum1z82
PubMed
UniProtA0A0F6AK91|GPDA_THESQ Glycerol-3-phosphate dehydrogenase [NAD(P)+] (Gene Name=gpsA)

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