Structure of PDB 1z59 Chain A

Receptor sequence
>1z59A (length=462) Species: 2286 (Saccharolobus shibatae) [Search protein sequence]
SLSPAEFFKRNPELAGFPNPARALYQTVRELIENSLDATDVHGILPNIKI
TIDLIDDARQIYKVNVVDNGIGIPPQEVPNAFGRVLYSSKYVNRQTRGMY
GLGVKAAVLYSQMHQDKPIEIETSPVNSKRIYTFKLKIDINKNEPIIVER
GSVENTRGFHGTSVAISIPGDWPKAKSRIYEYIKRTYIITPYAEFIFKDP
EGNVTYYPRLTNKIPKPPQEVKPHPYGVDREEIKILINNLKRDYTIKEFL
VNEFQSIGDTTADKILELAGLKPNKKVKNLTEEEITRLVETFKKYEDFRS
PSADSLSVIGEDLIELGLKKIFNPDFAASITRKPKAYQGHPFIVEAGVAF
GGSIPVGEEPIVLRYANKIPLIYDEKSDVIWKVVEELDWKRYGIESDQYQ
MVVMVHLCSTKIPYKSAGKESIAEVEDIEKEIKNALMEVARKLKQYLSEK
RKEQEAKKKLLA
3D structure
PDB1z59 Structural dissection of ATP turnover in the prototypical GHL ATPase TopoVI.
ChainA
Resolution2.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A N42 A46 I81 A89 V112 N34 A38 I73 A81 V104
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity
GO:0005524 ATP binding
Biological Process
GO:0006265 DNA topological change

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1z59, PDBe:1z59, PDBj:1z59
PDBsum1z59
PubMed15939019
UniProtO05207|TOP6B_SACSH Type 2 DNA topoisomerase 6 subunit B (Gene Name=top6B)

[Back to BioLiP]