Structure of PDB 1yzq Chain A

Receptor sequence
>1yzqA (length=164) Species: 9606 (Homo sapiens) [Search protein sequence]
FKLVFLGEQSVGKTSLITRFMYDSFDNTYQATIGIDFLSKTMYLEDRTIR
LQLWDTAGQERFRSLIPSYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRT
ERGSDVIIMLVGNKTDLADKRQVSIEEGERKAKELNVMFIETSAKAGYNV
KQLFRRVAAALPGM
3D structure
PDB1yzq Structural basis of family-wide Rab GTPase recognition by rabenosyn-5.
ChainA
Resolution1.78 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Q72
Catalytic site (residue number reindexed from 1) Q59
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG A T27 T45 T14 T32
BS02 GNP A Q22 S23 V24 G25 K26 T27 S28 F38 N40 Y42 T45 G71 N126 K127 D129 L130 S156 A157 K158 Q9 S10 V11 G12 K13 T14 S15 F25 N27 Y29 T32 G58 N113 K114 D116 L117 S143 A144 K145
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:1yzq, PDBe:1yzq, PDBj:1yzq
PDBsum1yzq
PubMed16034420
UniProtP20340|RAB6A_HUMAN Ras-related protein Rab-6A (Gene Name=RAB6A)

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