Structure of PDB 1yyo Chain A

Receptor sequence
>1yyoA (length=220) Species: 63363 (Aquifex aeolicus) [Search protein sequence]
MKMLEQLEKKLGYTFKDKSLLEKALTHVSYSKKEHYETLEFLGDALVNFF
IVDLLVQYSPNKREGFLSPLKAYLISEEFFNLLAQKLELHKFIRIKRGKI
NETIIGDVFKALWAAVYIDSGRDANFTRELFYKLFKEDILSAIKEGRVKK
DYKTILQEITQKRWKERPEYRLISVEGPHHKKKFIVEAKIKEYRTLGEGK
SKKEAEQRAAEELIKLLEES
3D structure
PDB1yyo Intermediate states of ribonuclease III in complex with double-stranded RNA
ChainA
Resolution2.9 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.26.3: ribonuclease III.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A D151 K153 T154 Q157 R167 K203 D151 K153 T154 Q157 R167 K203
BS02 rna A E158 Q161 E158 Q161
BS03 rna A H179 H180 H179 H180
BS04 rna A H180 K182 F184 K200 S201 K202 H180 K182 F184 K200 S201 K202
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0004519 endonuclease activity
GO:0004525 ribonuclease III activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006364 rRNA processing
GO:0006396 RNA processing
GO:0006397 mRNA processing
GO:0008033 tRNA processing
GO:0010468 regulation of gene expression
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1yyo, PDBe:1yyo, PDBj:1yyo
PDBsum1yyo
PubMed16216575
UniProtO67082|RNC_AQUAE Ribonuclease 3 (Gene Name=rnc)

[Back to BioLiP]