Structure of PDB 1yxh Chain A

Receptor sequence
>1yxhA (length=119) Species: 195058 (Naja sagittifera) [Search protein sequence]
NIYQFKNMIQCTVPSRSWWDFADYGCYCGRGGSGTPVDDLDRCCQVHDNC
YNQAQEITGCRPKWKTYTYECSQGTLTCKGRNNACAATVCDCDRLAAICF
AGAPYNDNNYNIDLKARCQ
3D structure
PDB1yxh Crystal structure of a novel phospholipase A(2) from Naja naja sagittifera with a strong anticoagulant activity
ChainA
Resolution1.86 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Y28 G30 G32 H48 D49 Y52 Y68 D94
Catalytic site (residue number reindexed from 1) Y27 G29 G31 H47 D48 Y51 Y67 D93
Enzyme Commision number 3.1.1.4: phospholipase A2.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A Y28 G30 G32 D49 Y27 G29 G31 D48
Gene Ontology
Molecular Function
GO:0004623 phospholipase A2 activity
GO:0005509 calcium ion binding
Biological Process
GO:0006644 phospholipid metabolic process
GO:0016042 lipid catabolic process
GO:0050482 arachidonate secretion

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Molecular Function
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Biological Process
External links
PDB RCSB:1yxh, PDBe:1yxh, PDBj:1yxh
PDBsum1yxh
PubMed16269164
UniProtQ6T179|PA2A4_NAJSG Acidic phospholipase A2 4 (Fragment)

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