Structure of PDB 1yvg Chain A

Receptor sequence
>1yvgA (length=397) Species: 1513 (Clostridium tetani) [Search protein sequence]
PITINNFRYSDPVNNDTIIMMEPPYCKGLDIYYKAFKITDRIWIVPERYE
FGTKPEDFNPPSSASEYYDPNYLRTDSDKDRFLQTMVKLFNRIKNNVAGE
ALLDKIINAIPYLGNSYSLLDKFDTNSNSVSFNLLEQDPSGATTKSAMLT
NLIIFGPGPVLNKNEVRGIVLRVDNKNYFPCRDGFGSIMQMAFCPEYVPT
FDNSKYFQDPALLLMHELIHVLHGLYGMQVSSHEIPISAEELFTFGGQDA
NLISIDIKNDLYEKTLNDYKAIANKLSQVTSCNDPNIDIDSYKQIYQQKY
QFDKDSNGQYIVNEDKFQILYNSIMYGFTEIELGKKFNIKTRLSYFSMNH
DPVKIPNLLDDTIYNDTEGFNIESKDLKSEYKGQNMRVNTNAFRNVD
3D structure
PDB1yvg Structural analysis of the catalytic domain of tetanus neurotoxin.
ChainA
Resolution2.6 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) H232 E233 H236 E270 R371
Catalytic site (residue number reindexed from 1) H216 E217 H220 E241 R342
Enzyme Commision number 3.4.24.68: tentoxilysin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H232 H236 E270 H216 H220 E241
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:1yvg, PDBe:1yvg, PDBj:1yvg
PDBsum1yvg
PubMed15904688
UniProtP04958|TETX_CLOTE Tetanus toxin (Gene Name=tetX)

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