Structure of PDB 1yrk Chain A

Receptor sequence
>1yrkA (length=126) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHMAPFLRIAFNSYELGSLQAEDEANQPFCAVKMKEALSTERGKTLVQK
KPTMYPEWKSTFDAHIYEGRVIQIVLMRAAEEPVSEVTVGVSVLAERCKK
NNGKAEFWLDLQPQAKVLMSVQYFLE
3D structure
PDB1yrk The C2 domain of PKCdelta is a phosphotyrosine binding domain.
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
2.7.11.13: protein kinase C.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A F4 R6 K48 P49 M51 Y52 D60 A61 H62 R67 F121 L122 E123 F7 R9 K51 P52 M54 Y55 D63 A64 H65 R70 F124 L125 E126
External links
PDB RCSB:1yrk, PDBe:1yrk, PDBj:1yrk
PDBsum1yrk
PubMed15851022
UniProtQ05655|KPCD_HUMAN Protein kinase C delta type (Gene Name=PRKCD)

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