Structure of PDB 1yow Chain A

Receptor sequence
>1yowA (length=230) Species: 9606 (Homo sapiens) [Search protein sequence]
SNVPELMLQLLQLEPDEDQVRARILGCLQEPAAFGLLCRMADQTFISIVD
WARRCMVFKELEVADQMTLLQNCWSELLVFDHIYRQVQHGKEGSILLVTG
QEVELTTVATQAGSLLHSLVLRAQELVLQLLALQLDRQEFVCLKFIILFS
LDLKFLNNHILVKDAQEKANAALLDYTLCHYPHCGDKFQQLLLCLVEVRA
LSMQAKEYLYHKHLGNEMPRNNLLIEMLQA
3D structure
PDB1yow Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1
ChainA
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q294 M295 E454 M455 Q66 M67 E226 M227
BS02 P0E A F262 S303 L306 V307 H310 I323 V336 G341 L344 S430 A433 Y436 K440 F34 S75 L78 V79 H82 I95 V108 G113 L116 S202 A205 Y208 K212
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity

View graph for
Molecular Function
External links
PDB RCSB:1yow, PDBe:1yow, PDBj:1yow
PDBsum1yow
PubMed15707893
UniProtQ13285|STF1_HUMAN Steroidogenic factor 1 (Gene Name=NR5A1)

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