Structure of PDB 1ymt Chain A

Receptor sequence
>1ymtA (length=235) Species: 10090 (Mus musculus) [Search protein sequence]
GSSGGPNVPELILQLLQLEPEEDQVRARIVGCLQQPAPFSLLCRMADQTF
ISIVDWARRCMVFKELEVADQMTLLQNSWSELLVLDHIYRQVQYGKEDSI
LLVTGQEVELSTVAVQAGSLLHSLVLRAQELVLQLHALQLDRQEFVCLKF
LILFSLDVKFLNNHSLVKDAQEKANAALLDYTLSHYPHSGDKFQQLLLSL
VEVRALSMQAKEYLYHKHLGNEMPRNNLLIEMLQA
3D structure
PDB1ymt Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1
ChainA
Resolution1.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A M296 E455 M72 E231
BS02 DR9 A A261 F263 L266 C267 M269 S304 Q340 A341 G342 L345 L348 A434 Y437 L438 K441 A37 F39 L42 C43 M45 S80 Q116 A117 G118 L121 L124 A210 Y213 L214 K217
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity

View graph for
Molecular Function
External links
PDB RCSB:1ymt, PDBe:1ymt, PDBj:1ymt
PDBsum1ymt
PubMed15707893
UniProtP33242|STF1_MOUSE Steroidogenic factor 1 (Gene Name=Nr5a1)

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