Structure of PDB 1ymm Chain A

Receptor sequence
>1ymmA (length=182) Species: 9606 (Homo sapiens) [Search protein sequence]
KEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRF
ASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELRE
PNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYL
PFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAP
3D structure
PDB1ymm Unconventional topology of self peptide-major histocompatibility complex binding by a human autoimmune T cell receptor.
ChainA
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Q9 E11 R50 F51 A52 S53 F54 G58 N62 N69 I72 Q8 E10 R49 F50 A51 S52 F53 G57 N61 N68 I71
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1ymm, PDBe:1ymm, PDBj:1ymm
PDBsum1ymm
PubMed15821740
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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