Structure of PDB 1ylh Chain A

Receptor sequence
>1ylhA (length=524) Species: 67854 (Actinobacillus succinogenes) [Search protein sequence]
DLNKLVKELNDLGLTDVKEIVYNPSYEQLFEEETKPGLEGFDKGTLTTLG
AVAVDTGIFTGRSPKDKYIVCDETTKDTVWWNSEAAKNDNKPMTQETWKS
LRELVAKQLSGKRLFVVEGYCGASEKHRIGVRMVTEVAWQAHFVKNMFIR
PTDEELKNFKADFTVLNGAKCTNPNWKEQGLNSENFVAFNITEGIQLIGG
TWYGGEMKKGMFSMMNYFLPLKGVASMHCSANVGKDGDVAIFFGLSGTGK
TTLSTDPKRQLIGDDEHGWDESGVFNFEGGCYAKTINLSQENEPDIYGAI
RRDALLENVVVRADGSVDFDDGSKTENTRVSYPIYHIDNIVRPVSKAGHA
TKVIFLTADAFGVLPPVSKLTPEQTEYYFLSGFTAPTPTFSACFGAAFLS
LHPIQYADVLVERMKASGAEAYLVNTGWNGTGKRISIKDTRGIIDAILDG
SIEKAEMGELPIFNLAIPKALPGVDPAILDPRDTYADKAQWQVKAEDLAN
RFVKNFVKYTANPEAAKLVGAGPK
3D structure
PDB1ylh Structure of PEP carboxykinase from the succinate-producing Actinobacillus succinogenes: a new conserved active-site motif.
ChainA
Resolution1.7 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R65 K213 H232 S250 K254 T255 D269 R333
Catalytic site (residue number reindexed from 1) R62 K209 H228 S246 K250 T251 D265 R329
Enzyme Commision number 4.1.1.49: phosphoenolpyruvate carboxykinase (ATP).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A K213 H232 D269 K209 H228 D265
BS02 PO4 A R154 Y339 R346 R150 Y335 R342
BS03 DT3 A L108 K111 Q112 C175 T176 L104 K107 Q108 C171 T172
BS04 PYR A R65 Y207 R333 R62 Y203 R329
Gene Ontology
Molecular Function
GO:0004611 phosphoenolpyruvate carboxykinase activity
GO:0004612 phosphoenolpyruvate carboxykinase (ATP) activity
GO:0005524 ATP binding
GO:0016831 carboxy-lyase activity
GO:0017076 purine nucleotide binding
GO:0046872 metal ion binding
Biological Process
GO:0006094 gluconeogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Cellular Component
External links
PDB RCSB:1ylh, PDBe:1ylh, PDBj:1ylh
PDBsum1ylh
PubMed15983413
UniProtA6VKV4|PCKA_ACTSZ Phosphoenolpyruvate carboxykinase (ATP) (Gene Name=pckA)

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