Structure of PDB 1yk1 Chain A

Receptor sequence
>1yk1A (length=394) Species: 9606 (Homo sapiens) [Search protein sequence]
ALPPQKIEVLVLLPQDDSYLFSLTRVRPAIEYALRSVEGLLPPGTRFQVA
YEDSDCGNRALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDL
PMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAAL
VYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQ
ASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDGSW
KRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMED
YVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAG
QVSIDANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRP
3D structure
PDB1yk1 Structural determinants of natriuretic peptide receptor specificity and degeneracy.
ChainA
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A E92 Y93 A96 R100 G118 F119 E125 Y169 E173 H176 E85 Y86 A89 R93 G111 F112 E118 Y162 E166 H169
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:1yk1, PDBe:1yk1, PDBj:1yk1
PDBsum1yk1
PubMed16870210
UniProtP17342|ANPRC_HUMAN Atrial natriuretic peptide receptor 3 (Gene Name=NPR3)

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