Structure of PDB 1yk0 Chain A

Receptor sequence
>1yk0A (length=394) Species: 9606 (Homo sapiens) [Search protein sequence]
ALPPQKIEVLVLLPQDDSYLFSLTRVRPAIEYALRSVEGLLPPGTRFQVA
YEDSDCGNRALFSLVDRVAAARGAKPDLILGPVCEYAAAPVARLASHWDL
PMLSAGALAAGFQHKDSEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAAL
VYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQ
ASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDGSW
KRGDKHDFEAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGLNMED
YVNMFVEGFHDAILLYVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAG
QVSIDANGDRYGDFSVIAMTDVEAGTQEVIGDYFGKEGRFEMRP
3D structure
PDB1yk0 Structural determinants of natriuretic peptide receptor specificity and degeneracy.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y93 A96 R100 A116 A117 G118 H121 E125 Y159 K163 R166 Y169 F170 E173 H176 E177 I188 Y86 A89 R93 A109 A110 G111 H114 E118 Y152 K156 R159 Y162 F163 E166 H169 E170 I181
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:1yk0, PDBe:1yk0, PDBj:1yk0
PDBsum1yk0
PubMed16870210
UniProtP17342|ANPRC_HUMAN Atrial natriuretic peptide receptor 3 (Gene Name=NPR3)

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