Structure of PDB 1ybu Chain A

Receptor sequence
>1ybuA (length=166) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
AERMLATIMFTDIVGSTQHAAALGDDRWRDLLDNHDTIVCHEIQRFGGRE
VNTAGDGFVATFTSPSAAIACADDIVDAVAALGIEVRIGIHAGEVEVRDA
SHGTDVAGVAVHIGARVCALAGPSEVLVSSTVRDIVAGSRHRFAERGEQE
LKGVPGRWRLCVLMRD
3D structure
PDB1ybu Origin of asymmetry in adenylyl cyclases: structures of Mycobacterium tuberculosis Rv1900c.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.1.-
4.6.1.1: adenylate cyclase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MN A D302 I303 S306 D346 D12 I13 S16 D56
BS02 APC A D302 G305 G345 D346 D12 G15 G55 D56
Gene Ontology
Biological Process
GO:0009190 cyclic nucleotide biosynthetic process
GO:0035556 intracellular signal transduction

View graph for
Biological Process
External links
PDB RCSB:1ybu, PDBe:1ybu, PDBj:1ybu
PDBsum1ybu
PubMed15678099
UniProtO07732|LIPJ_MYCTU Bifunctional lipase/adenylate cyclase LipJ (Gene Name=lipJ)

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