Structure of PDB 1yb6 Chain A

Receptor sequence
>1yb6A (length=256) Species: 3981 (Hevea brasiliensis) [Search protein sequence]
AFAHFVLIHTICHGAWIWHKLKPLLEALGHKVTALDLAASGVDPRQIEEI
GSFDEYSEPLLTFLEALPPGEKVILVGESCGGLNIAIAADKYCEKIAAAV
FHNSVLPDTEHCPSYVVDKLMEVFPDWKDTTYFTYTKDGKEITGLKLGFT
LLRENLYTLCGPEEYELAKMLTRKGSLFQNILAKRPFFTKEGYGSIKKIY
VWTDQDEIFLPEFQLWQIENYKPDKVYKVEGGDHKLQLTKTKEIAEILQE
VADTYN
3D structure
PDB1yb6 Structural determinants of the enantioselectivity of the hydroxynitrile lyase from Hevea brasiliensis
ChainA
Resolution1.54 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) T11 S80 C81 D207 H235 K236
Catalytic site (residue number reindexed from 1) T10 S79 C80 D206 H234 K235
Enzyme Commision number 4.1.2.47: (S)-hydroxynitrile lyase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MNN A T11 S80 W128 L148 L157 I209 H235 K236 T10 S79 W127 L147 L156 I208 H234 K235
Gene Ontology
Molecular Function
GO:0016829 lyase activity
GO:0047606 (S)-hydroxynitrile lyase activity
GO:0052891 aliphatic (S)-hydroxynitrile lyase activity
GO:0052892 aromatic (S)-hydroxynitrile lyase activity
GO:0080030 methyl indole-3-acetate esterase activity
GO:0080031 methyl salicylate esterase activity
GO:0080032 methyl jasmonate esterase activity
Biological Process
GO:0009694 jasmonic acid metabolic process
GO:0009696 salicylic acid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:1yb6, PDBe:1yb6, PDBj:1yb6
PDBsum1yb6
PubMed17250917
UniProtP52704|HNL_HEVBR (S)-hydroxynitrile lyase (Gene Name=HNL)

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