Structure of PDB 1yak Chain A

Receptor sequence
>1yakA (length=219) Species: 1423 (Bacillus subtilis) [Search protein sequence]
KFSEECRSAAAEWWEGSFVHPFVQGIGDGTLPIDRFKYYVLQDSYYLTHF
AKVQSFGAAYAKDLYTTGRMASHAQGTYEAEMALHREFAELLEISEEERK
AFKPSPTAYSYTSHMYRSVLSGNFAEILAALLPCYWLYYEVGEKLLHCDP
GHPIYQKWIGTYGGDWFRQQVEEQINRFDELAENSTEEVRAKMKENFVIS
SYYEYQFWGMAYRKEGWSD
3D structure
PDB1yak Structural characterization of the regulatory proteins TenA and TenI from Bacillus subtilis and identification of TenA as a thiaminase II.
ChainA
Resolution2.5 Å
3D
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Enzymatic activity
Enzyme Commision number 3.5.99.2: aminopyrimidine aminohydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 HMH A D44 Y47 C135 Y139 Y163 E205 D43 Y46 C134 Y138 Y162 E204
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0050334 thiaminase activity
Biological Process
GO:0006772 thiamine metabolic process
GO:0006790 sulfur compound metabolic process
GO:0009228 thiamine biosynthetic process
GO:0009229 thiamine diphosphate biosynthetic process
GO:0044281 small molecule metabolic process
GO:1901615 organic hydroxy compound metabolic process
Cellular Component
GO:0005829 cytosol

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Cellular Component
External links
PDB RCSB:1yak, PDBe:1yak, PDBj:1yak
PDBsum1yak
PubMed15709744
UniProtP25052|TENA_BACSU Aminopyrimidine aminohydrolase (Gene Name=tenA)

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