Structure of PDB 1y20 Chain A

Receptor sequence
>1y20A (length=287) Species: 10116 (Rattus norvegicus) [Search protein sequence]
RLKIVTIHQEPFVYVKPTMSDGTCKEEFTVNGDPVKKVICTGPNDTSPGS
PRHTVPQCCYGFCIDLLIKLARTMNFTYEVHLVADGKFGTQERVNNSNKK
EWNGMMGELLSGQADMIVAPLTINNERAQYIEFSKPFKYQGLTILVKKGT
RITGINDPRLRNPSDKFIYATVKQSSVDIYFRRQVELSTMYRHMEKHNYE
SAAEAIQAVRDNKLHAFIWDSAVLEFEASQKCDLVTTGELFFRSGFGIGM
RKDSPWKQNVSLSILKSHENGFMEDLDKTWVRYQECD
3D structure
PDB1y20 Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors.
ChainA
Resolution1.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 1AC A F92 L125 T126 R131 S179 S180 W223 D224 F88 L121 T122 R127 S175 S176 W219 D220 MOAD: Ki=4.8uM
PDBbind-CN: -logKd/Ki=5.32,Ki=4.8uM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:1y20, PDBe:1y20, PDBj:1y20
PDBsum1y20
PubMed15996549
UniProtP35439|NMDZ1_RAT Glutamate receptor ionotropic, NMDA 1 (Gene Name=Grin1)

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