Structure of PDB 1xuz Chain A

Receptor sequence
>1xuzA (length=348) Species: 487 (Neisseria meningitidis) [Search protein sequence]
QNNNEFKIGNRSVGYNHEPLIICEIGINHEGSLKTAFEMVDAAYNAGAEV
VKHQTHIVEDEMSDEAKQVIPGNADVSIYEIMERCALNEEDEIKLKEYVE
SKGMIFISTPFSRAAALRLQRMDIPAYKIGSGECNNYPLIKLVASFGKPI
ILSTGMNSIESIKKSVEIIREAGVPYALLHCTNIYPTPYEDVRLGGMNDL
SEAFPDAIIGLSDHTLDNYACLGAVALGGSILERHFTDRMDRPGPDIVCS
MNPDTFKELKQGAHALKLARGGKKDTIIAGEKPTKDFAFASVVADKDIKK
GELLSGDNLWVKRPGNGDFSVNEYETLFGKVAACNIRKGAQIKKTDIE
3D structure
PDB1xuz Structural and mechanistic analysis of sialic acid synthase NeuB from Neisseria meningitidis in complex with Mn2+, phosphoenolpyruvate, and N-acetylmannosaminitol.
ChainA
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 MMN A Q55 N74 Y186 H236 D247 Q54 N73 Y185 H235 D246
BS02 MN A H215 H236 H214 H235
BS03 PEP A K53 Q55 T110 K129 G131 S132 S154 C182 S213 H215 K52 Q54 T109 K128 G130 S131 S153 C181 S212 H214
Gene Ontology
Molecular Function
GO:0046872 metal ion binding
GO:0047444 N-acylneuraminate-9-phosphate synthase activity
Biological Process
GO:0016051 carbohydrate biosynthetic process
GO:0070085 glycosylation

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Molecular Function
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Biological Process
External links
PDB RCSB:1xuz, PDBe:1xuz, PDBj:1xuz
PDBsum1xuz
PubMed15516336
UniProtQ57265

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