Structure of PDB 1xtj Chain A

Receptor sequence
>1xtjA (length=374) Species: 9606 (Homo sapiens) [Search protein sequence]
SGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMG
KTAVFVLATLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVK
VAVFFGGLSIKKDEEVLKKNCPHIVVGTPGRILALARNKSLNLKHIKHFI
LDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATLSKEIRPVCRKFMQ
DPMEIFVDDETKLTLHGLQQYYVKLKDNEKNRKLFDLLDVLEFNQVVIFV
KSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVAT
NLDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKI
LNDVQDRFEVNISELPDEIDISSY
3D structure
PDB1xtj Crystal structure of the human ATP-dependent splicing and export factor UAP56
ChainA
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A F65 H67 Q72 G92 G94 K95 T96 F21 H23 Q28 G48 G50 K51 T52
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003724 RNA helicase activity
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:1xtj, PDBe:1xtj, PDBj:1xtj
PDBsum1xtj
PubMed15585580
UniProtQ13838|DX39B_HUMAN Spliceosome RNA helicase DDX39B (Gene Name=DDX39B)

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