Structure of PDB 1xru Chain A

Receptor sequence
>1xruA (length=281) Species: 562 (Escherichia coli) [Search protein sequence]
GSAMDVRQSIHSAHAKTLDTQGLRNEFLVEKVFVADEYTMVYSHIDRIIV
GGIMPITKTVSVGGEVGKQLGVSYFLERRELGVINIGGAGTITVDGQCYE
IGHRDALYVGKGAKEVVFASIDTGTPAKFYYNCAPAHTTYPTKKVTPDEV
SPVTLGDNLTSNRRTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHT
HERRMEVYFYFNMDDDACVFHMMGQPQETRHIVMHNEQAVISPSWSIHSG
VGTKAYTFIWGMVGENQVFDDMDHVAVKEIC
3D structure
PDB1xru The crystal structure of 5-keto-4-deoxyuronate isomerase from Escherichia coli
ChainA
Resolution1.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 5.3.1.17: 5-dehydro-4-deoxy-D-glucuronate isomerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H196 H198 E203 H245 H199 H201 E206 H248
Gene Ontology
Molecular Function
GO:0004347 glucose-6-phosphate isomerase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0008697 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity
GO:0016853 isomerase activity
GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0019698 D-galacturonate catabolic process
GO:0042840 D-glucuronate catabolic process
GO:0045490 pectin catabolic process
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1xru, PDBe:1xru, PDBj:1xru
PDBsum1xru
PubMed16152643
UniProtQ46938|KDUI_ECOLI 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase (Gene Name=kduI)

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