Structure of PDB 1xr8 Chain A

Receptor sequence
>1xr8A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHSMRYFYTAMSRPGRGEPRFIAVGYVDDTQFVRFDSDAASPRMAPRAP
WIEQEGPEYWDRETQISKTNTQTYRESLRNLRGYYNQSEAGSHTLQRMYG
CDVGPDGRLLRGHDQSAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
REAEQWRAYLEGLCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
3D structure
PDB1xr8 Crystal structures of two peptide-HLA-B*1501 complexes; structural characterization of the HLA-B62 supertype
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A Y7 Y9 M45 R62 E63 I66 E76 S77 Y84 R97 Y99 S116 T143 K146 W147 W156 Y159 W167 Y171 Y7 Y9 M45 R62 E63 I66 E76 S77 Y84 R97 Y99 S116 T143 K146 W147 W156 Y159 W167 Y171
External links
PDB RCSB:1xr8, PDBe:1xr8, PDBj:1xr8
PDBsum1xr8
PubMed17057332
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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