Structure of PDB 1xiu Chain A

Receptor sequence
>1xiuA (length=221) Species: 6526 (Biomphalaria glabrata) [Search protein sequence]
NDMPVEQILEAELAVDPKIDTYIDAQKDPVTNICQAADKQLFTLVEWAKR
IPHFTELPLEDQVILLRAGWNELLIAGFSHRSIMAKDGILLATGLHVHRS
SAHQAGVGTIFDRVLTELVAKMRDMKMDKTELGCLRAVVLFNPDAKGLTA
VQEVEQLREKVYASLEEYTKSRYPEEPGRFAKLLLRLPALRSIGLKCLEH
LFFFKLIGDQPIDTFLMEMLE
3D structure
PDB1xiu Crystal Structure of a Novel Tetrameric Complex of Agonist-bound Ligand-binding Domain of Biomphalaria glabrata Retinoid X Receptor.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A K258 L268 V272 R276 K49 L59 V63 R67
BS02 9CR A I242 A245 A246 Q249 F287 R290 L300 A301 V316 C406 I33 A36 A37 Q40 F78 R81 L91 A92 V107 C197
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003707 nuclear steroid receptor activity
GO:0008270 zinc ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1xiu, PDBe:1xiu, PDBj:1xiu
PDBsum1xiu
PubMed16274693
UniProtQ8T5C6|RXR_BIOGL Retinoic acid receptor RXR (Gene Name=RXR)

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