Structure of PDB 1xhy Chain A

Receptor sequence
>1xhyA (length=259) Species: 10116 (Rattus norvegicus) [Search protein sequence]
KTVVVTTILESPYVMMKKNHEMLEGNERYEGYCVDLAAEIAKHCGFKYKL
TIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFS
KPFMSLGISIMIKKGTPIESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIA
VFDKMWTYMRSAEPSVFVRTTAEGVARVRKSKGKYAFLLESTMNEYIEQR
KPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKLKNK
WWYDKGECG
3D structure
PDB1xhy Tyr702 Is an Important Determinant of Agonist Binding and Domain Closure of the Ligand-Binding Core of GluR2.
ChainA
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 KAI A Y58 P86 T88 R93 G138 S139 T140 E190 Y58 P86 T88 R93 G138 S139 T140 E190 MOAD: Ki=624nM
PDBbind-CN: -logKd/Ki=6.18,Ki=662nM
BindingDB: EC50=380000nM,Ki=3690nM
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:1xhy, PDBe:1xhy, PDBj:1xhy
PDBsum1xhy
PubMed15591246
UniProtP19491|GRIA2_RAT Glutamate receptor 2 (Gene Name=Gria2)

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