Structure of PDB 1xgm Chain A

Receptor sequence
>1xgmA (length=295) Species: 2261 (Pyrococcus furiosus) [Search protein sequence]
MDTEKLMKAGEIAKKVREKAIKLARPGMLLLELAESIEKMIMELGGKPAF
PVNLSINEIAAHYTPYKGDTTVLKEGDYLKIDVGVHIDGFIADTAVTVRV
GMEEDELMEAAKEALNAAISVARAGVEIKELGKAIENEIRKRGFKPIVNL
SGHKIERYKLHAGISIPNIYRPHDNYVLKEGDVFAIEPFATIGAGQVIEV
PPTLIYMYVRDVPVRVAQARFLLAKIKREYGTLPFAYRWLQNDMPEGQLK
LALKTLEKAGAIYGYPVLKEIRNGIVAQFEHTIIVEKDSVIVTTE
3D structure
PDB1xgm Crystal structure of methionine aminopeptidase from hyperthermophile, Pyrococcus furiosus.
ChainA
Resolution2.8 Å
3D
structure
Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Catalytic site (original residue number in PDB) D82 D93 H153 H161 E187 E280
Catalytic site (residue number reindexed from 1) D82 D93 H153 H161 E187 E280
Enzyme Commision number 3.4.11.18: methionyl aminopeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CO A D93 H153 E187 E280 D93 H153 E187 E280
BS02 CO A D82 D93 E187 E280 D82 D93 E187 E280
Gene Ontology
Molecular Function
GO:0004177 aminopeptidase activity
GO:0004239 initiator methionyl aminopeptidase activity
GO:0008235 metalloexopeptidase activity
GO:0046872 metal ion binding
GO:0070006 metalloaminopeptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1xgm, PDBe:1xgm, PDBj:1xgm
PDBsum1xgm
PubMed9811545
UniProtP56218|MAP2_PYRFU Methionine aminopeptidase (Gene Name=map)

[Back to BioLiP]