Structure of PDB 1xez Chain A

Receptor sequence
>1xezA (length=663) Species: 666 (Vibrio cholerae) [Search protein sequence]
AIKYYNAADWQALPSLAELRDLVINQQKRVLVDFSQISDAEGQAEMQAQF
RKAYGVGFANQFIVITEHKGELLFTPFDRTEETNTLPHVAFYISVNRAIS
DEECTFNNSWLWKNEKGSRPFCKDANISLIYRVNLERSLQYGIVGSATPD
AKIVRISLDDDSTGAGIHLNDQLGYRQFGASYTTLDAYFREWSTDAIAQD
YRFVFNASNNKAQILKTFPVDNINEKFERKEVSGFELGVTGGVEVSGDGP
KAKLEARASYTQSRWLTYNTQDYRIERNAKNAQAVSFTWNRQQYATAESL
LNRSTDALWVNTYPVDVNRISPLSYASFVPKMDVIYKASATETGSTDFII
DSSVNIRPIYNGAYKHYYVVGAHQSYHGFEDTPRRRITKSASFTVDWDHP
VFTGGRPVNLQLASFNNRCIQVDAQGRLTANMCDSQQSAQSFIYDQLGRY
VSASNTKLCLDGAALDALQPCNQNLTQRWEWRKGTDELTNVYSGESLGHD
KQTGELGLYASSNDAVSLRTITAYTDVFNAQESSPILGYTQGKMNQQRVG
QDNRLYVRAGAAIDALGSASDLLVGGNGGSLSSVDLSGVKSITATSGDFQ
YGGQQLVALTFTYQDGRQQTVGSKAYVTNAHEDRFDLPDAAKITQLKIWA
DDWLVKGVQFDLN
3D structure
PDB1xez Crystal Structure of the Vibrio cholerae Cytolysin (VCC) Pro-toxin and its Assembly into a Heptameric Transmembrane Pore
ChainA
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 BOG A G613 A614 A615 D617 G631 G632 Y654 G560 A561 A562 D564 G578 G579 Y601
Gene Ontology
Biological Process
GO:0051715 cytolysis in another organism
Cellular Component
GO:0005576 extracellular region

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Biological Process

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Cellular Component
External links
PDB RCSB:1xez, PDBe:1xez, PDBj:1xez
PDBsum1xez
PubMed15978620
UniProtP09545|HLYA_VIBCH Hemolysin (Gene Name=hlyA)

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