Structure of PDB 1xex Chain A

Receptor sequence

>1xexA (length=166) Species: 2261 (Pyrococcus furiosus) [Search protein sequence]

PYIEKLELKGFKSYGNKKVVIPFSKGFTAIVGANGSGKSNIGDAILFVLG
GLSAKAMRASRISDLIFAGSKNEPPAKYAEVAIYFNNEDRGFPIDEDEVV
IRRRVYPDGRSSYWLNGRRATRSEILDILTAAMISPDGYNIVLQGDITKF
IKMSPLERRLLIDDIS

3D structure

PDB

1xex Structural biochemistry of ATP-driven dimerization and DNA-stimulated activation of SMC ATPases

Chain

Resolution

2.5 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	MG	A	S40 Q145	S39 Q144
BS02	ATP	A	K13 S14 N35 G36 G38 K39 S40 N41 R59 I67 F68 A69 Q145	K12 S13 N34 G35 G37 K38 S39 N40 R58 I66 F67 A68 Q144

External links

PDB	RCSB:1xex, PDBe:1xex, PDBj:1xex
PDBsum	1xex
PubMed	15458651
UniProt	Q8TZY2\|SMC_PYRFU Chromosome partition protein Smc (Gene Name=smc)

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