Structure of PDB 1xbr Chain A

Receptor sequence
>1xbrA (length=184) Species: 8355 (Xenopus laevis) [Search protein sequence]
ELKVSLEERDLWTRFKELTNEMIVTKNGRRMFPVLKVSMSGLDPNAMYTV
LLDFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKDP
VSFSKVKLTNKMNGGGQIMLNSLHKYEPRIHIVRVGGTQRMITSHSFPET
QFIAVTAYQNEEITALKIKHNPFAKAFLDAKERN
3D structure
PDB1xbr Crystallographic structure of the T domain-DNA complex of the Brachyury transcription factor.
ChainA
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R99 K149 S160 T194 P210 K213 A214 R61 K111 S122 T156 P172 K175 A176
BS02 dna A R67 R68 Y196 N209 F211 F215 R29 R30 Y158 N171 F173 F177
Gene Ontology
Molecular Function
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0045893 positive regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1xbr, PDBe:1xbr, PDBj:1xbr
PDBsum1xbr
PubMed9349824
UniProtP24781|TBXT_XENLA T-box transcription factor T (Gene Name=tbxt)

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