Structure of PDB 1x8k Chain A

Receptor sequence
>1x8kA (length=344) Species: 7108 (Spodoptera frugiperda) [Search protein sequence]
DLPFPYEFRELNPEEDKLVKANLGAFPTTYVKLGPKGYMVYRPYLKDAAN
IYNMPLRPTDVFVASYQRSGTTMTQELVWLIENDLNFEAAKTYMSLRYIY
LDGFMIYDPEKQEEYNDILPNPENLDMERYLGLLEYSSRPGSSLLAAVPP
TEKRFVKTHLPLSLMPPNMLDTVKMVYLARDPRDVAVSSFHHARLLYLLN
KQSNFKDFWEMFHRGLYTLTPYFEHVKEAWAKRHDPNMLFLFYEDYLKDL
PGSIARIADFLGKKLSEEQIQRLSEHLNFEKFKNNGAVNMEDYREIGILA
DGEHFIRKGKAGCWRDYFDEEMTKQAEKWIKDNLKDTDLRYPNM
3D structure
PDB1x8k The structures of the unique sulfotransferase retinol dehydratase with product and inhibitors provide insight into enzyme mechanism and inhibition.
ChainA
Resolution2.75 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) R73 H164 S193
Catalytic site (residue number reindexed from 1) R68 H159 S188
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A E118 N121 D122 E113 N116 D117
BS02 ANR A F31 L138 L139 K162 H197 L201 F310 F26 L133 L134 K157 H192 L196 F305
BS03 A3P A R73 G75 T76 T77 M78 R185 S193 Y248 L282 F284 F287 R312 K313 G314 R68 G70 T71 T72 M73 R180 S188 Y243 L277 F279 F282 R307 K308 G309
Gene Ontology
Molecular Function
GO:0008146 sulfotransferase activity
GO:0016740 transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0051923 sulfation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1x8k, PDBe:1x8k, PDBj:1x8k
PDBsum1x8k
PubMed15608121
UniProtQ26490

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