Structure of PDB 1x7p Chain A

Receptor sequence
>1x7pA (length=265) Species: 1938 (Streptomyces viridochromogenes) [Search protein sequence]
RNARFQQWQALLGNRNKRTRAGEFLVMGVRPISLAVEHGWPVRTLLYDGQ
RELSKWARELLRTVRTEQIAMAPDLLMELGEKNEAPPEVVAVVEMPADDL
DRIPVREDFLGVLFDRPTSPGNIGSIIRSADALGAHGLIVAGHAADVYDP
KSVRSSTGSLFSLPAVRVPSPGEVMDWVEARRAAGTPIVLVGTDEHGDCD
VFDFDFTQPTLLLIGNETAGLSNAWRTLCDYTVSIPMAGSASSLNAANAA
TAILYEAVRQRISGR
3D structure
PDB1x7p Structure and function of the antibiotic resistance-mediating methyltransferase AviRb from Streptomyces viridochromogenes
ChainA
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.208: 23S rRNA (uridine(2479)-2'-O)-methyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SAM A T210 D211 E212 G232 E234 G237 S251 I252 M254 L261 A263 A266 T193 D194 E195 G215 E217 G220 S234 I235 M237 L244 A246 A249
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0008168 methyltransferase activity
GO:0008173 RNA methyltransferase activity
GO:0008650 rRNA (uridine-2'-O-)-methyltransferase activity
Biological Process
GO:0006396 RNA processing
GO:0031167 rRNA methylation
GO:0032259 methylation
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:1x7p, PDBe:1x7p, PDBj:1x7p
PDBsum1x7p
PubMed15581897
UniProtQ9F5K6|AVRB_STRVR 23S rRNA (uridine(2479)-2'-O)-methyltransferase (Gene Name=aviRb)

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