Structure of PDB 1x2r Chain A

Receptor sequence
>1x2rA (length=290) Species: 10090 (Mus musculus) [Search protein sequence]
VGRLIYTAGGYFRQSLSYLEAYNPSNGSWLRLADLQVPRSGLAGCVVGGL
LYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGVIDG
HIYAVGGSHGCIHHSSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLY
AVGGFDGTNRLNSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAG
GYDGQDQLNSVERYDVETETWTFVAPMRHHRSALGITVHQGKIYVLGGYD
GHTFLDSVECYDPDSDTWSEVTRMTSGRSGVGVAVTMEPC
3D structure
PDB1x2r Structural basis for defects of keap1 activity provoked by its point mutations in lung cancer
ChainA
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A Y334 S363 N382 N387 R415 R483 S508 Y525 Q530 S555 Y572 F577 S602 Y11 S40 N59 N64 R92 R160 S185 Y202 Q207 S232 Y249 F254 S279
External links
PDB RCSB:1x2r, PDBe:1x2r, PDBj:1x2r
PDBsum1x2r
PubMed16507366
UniProtQ9Z2X8|KEAP1_MOUSE Kelch-like ECH-associated protein 1 (Gene Name=Keap1)

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